Cruise from California through the Panama Canal, one of the man-made wonders of the world. The canal is 100 years old but is still an awe inspiring engineering feat, and the best way to experience it is on a cruise.
Panama Canal cruises depart from Los Angeles, San Diego or San Francisco. They finish in Miami, Fort Lauderdale, Tampa or New York.
On your journey you'll visit tropical ports in countries like Mexico, Costa Rica and Colombia.
20-day Panama Canal cruise on Oceania. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Acjutla (El Salvador), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia), Santa Marta (Colombia), Oranjestad (Aruba) and Grand Cayman (Cayman Islands).
• 2020 departure: December 20.
16-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Cartagena (Colombia), Santa Marta (Colombia) and Oranjestad (Aruba).
• 2021 departure: January 22.
15-day Panama Canal cruise on Princess Cruises. One-way from San Francisco to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2021 departure: February 8.
18-day Panama Canal cruise on Holland America Line. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Manzanillo (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Fuerte Amador (Panama), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2021 departure: February 23.
15-day Panama Canal cruise on Princess Cruises. One-way from San Diego to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2021 departure: March 10.
16-day Panama Canal cruise on Holland America Line. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Curacao and Half Moon Cay (Bahamas).
• 2021 departure: March 25.
18-day Panama Canal cruise on Holland America Line. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Manzanillo (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Fuerte Amador (Panama), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2021 departure: March 30.
15-day Panama Canal cruise on Princess Cruises. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2021 departure: May 9.
16-night Panama Canal cruise on Celebrity Cruises. One-way from San Diego to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Colon (Panama) and Cartagena (Colombia).
• 2021 departure: September 26.
15-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Cartagena (Colombia) and Great Stirrup Cay (Bahamas).
• 2021 departure: October 6.
17-day Panama Canal cruise on Holland America Line. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Aruba, Curacao and Half Moon Cay (Bahamas).
• 2021 departure: October 7.
17-day Panama Canal cruise on Holland America Line. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Aruba, Curacao and Half Moon Cay (Bahamas).
• 2021 departure: October 8.
15-night Panama Canal cruise on Celebrity Cruises. One-way from San Diego to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Colon (Panama) and Cartagena (Colombia).
• 2021 departure: October 27.
17-day Panama Canal cruise on Norwegian Cruise Line. One-way from San Francisco to Miami (Florida). Visit San Diego (California), Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Panama City (Panama) and Cartagena (Colombia).
• 2021 departure: October 28.
14-night Panama Canal cruise on Disney Cruise Line. One-way from San Diego to Galveston (Texas). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), the Panama Canal, Cartagena (Colombia), Grand Cayman (Cayman Islands) and Cozumel (Mexico).
• 2021 departure: November 5.
14-day Panama Canal cruise on Holland America Line. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2021 departure: November 20.
11-day Panama Canal cruise on Norwegian Cruise Line. One-way from San Diego to Panama City (Panama). Visit Cabo San Lucas (Mexico), Puerto Quetzal (Guatemala), Acajutla (El Salvador), San Juan del Sur (Nicaragua) and Puntarenas (Costa Rica).
• 2022 departure: January 9.
14-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Panama City (Panama) and Cartagena (Colombia).
• 2022 departure: January 21.
15-day Panama Canal cruise on Princess Cruises. One-way from San Francisco to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2022 departure: February 25.
18-night Panama Canal cruise on Crystal Cruises. One-way from Los Angeles to New York. Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia), Key West (Florida) and Charleston (South Carolina).
• 2022 departure: August 15.
12-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to Panama City (Panama). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua) and Puntarenas (Costa Rica).
• 2022 departure: November 12.
