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Panama Canal

California Cruise Guide > Cruises > Panama Canal

Panama Canal Cruises from California

Cruise from California through the Panama Canal, one of the man-made wonders of the world. The canal is 100 years old but is still an awe inspiring engineering feat, and the best way to experience it is on a cruise.

Panama Canal cruises depart from Los Angeles, San Diego or San Francisco. They finish in Miami, Fort Lauderdale, Tampa or New York.

On your journey you'll visit tropical ports in countries like Mexico, Costa Rica and Colombia.

2024

15-night Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2024 departure: January 7.

16-night Panama Canal cruise on Regent Seven Seas. One-way from Los Angeles to Miami (Florida). Visit Ensenada (Mexico), Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2024 departure: January 8.

15-night Panama Canal cruise on Norwegian. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Manzanillo (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Panama City (Panama) and Cartagena (Colombia).
• 2024 departure: January 12.

15-night Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia) and Half Moon Cay (Bahamas).
• 2024 departure: January 19.

15-night Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2024 departure: February 6.

15-night Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia) and Half Moon Cay (Bahamas).
• 2024 departure: April 6.

15-night Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2024 departure: May 9.

15-night Panama Canal cruise on Celebrity. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2024 departure: September 19.

16-night Panama Canal cruise on Princess. One-way from San Francisco to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2024 departure: September 28.

14-night Panama Canal cruise on Royal Caribbean. One-way from Los Angeles to New Orleans (Louisiana). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), Puntarenas (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2024 departure: September 28.

15-night Panama Canal cruise on Carnival. One-way from San Francisco to Galveston (Texas). Visit Cabo San Lucas (Mexico), Puntarenas (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2024 departure: October 1.

16-night Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Puerto Caldera (Costa Rica), the Panama Canal, and Aruba.
• 2024 departure: October 4.

16-night Panama Canal cruise on Royal Caribbean. One-way from Los Angeles to Tampa (Florida). Visit Cabo San Lucas (Mexico), Mazatlan (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Colon (Panama), Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2024 departure: October 5.

16-night Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Puerto Caldera (Costa Rica), the Panama Canal, and Aruba.
• 2024 departure: October 10.

17-night Panama Canal cruise on Norwegian. One-way from Los Angeles to Tampa (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Manzanillo (Mexico), Zihuatanejo (Mexico), Puerto Chiapas (Mexico), Acajutla (El Salvador), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2024 departure: November 7.

16-night Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Manzanillo (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Aruba.
• 2024 departure: November 17.

15-night Panama Canal cruise on Norwegian. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Manzanillo (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Panama City (Panama) and Cartagena (Colombia).
• 2024 departure: December 6.

16-night Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Manzanillo (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Aruba.
• 2024 departure: December 19.

Panama Canal cruise from California
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